The absence of reactive oxygen species production protects mice against bleomycin-induced pulmonary fibrosis

BACKGROUND: Reactive oxygen species and tissue remodeling regulators, such as metalloproteinases (MMPs) and their inhibitors (TIMPs), are thought to be involved in the development of pulmonary fibrosis. We investigated these factors in the fibrotic response to bleomycin of p47(phox )-/- (KO) mice, d...

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Detalhes bibliográficos
Main Authors: Manoury, Boris, Nenan, Soazig, Leclerc, Olivier, Guenon, Isabelle, Boichot, Elisabeth, Planquois, Jean-Michel, Bertrand, Claude P, Lagente, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548519/
https://ncbi.nlm.nih.gov/pubmed/15663794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-11
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