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Mutational Analysis of Hepatitis C Virus Nonstructural Protein 5A: Potential Role of Differential Phosphorylation in RNA Replication and Identification of a Genetically Flexible Domain

Nonstructural protein 5A of the hepatitis C virus (HCV) is a highly phosphorylated molecule implicated in multiple interactions with the host cell and most likely involved in RNA replication. Two phosphorylated variants of NS5A have been described, designated according to their apparent molecular ma...

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Detalhes bibliográficos
Main Authors: Appel, Nicole, Pietschmann, Thomas, Bartenschlager, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548472/
https://ncbi.nlm.nih.gov/pubmed/15709040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.3187-3194.2005
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