Mutational Analysis of Hepatitis C Virus Nonstructural Protein 5A: Potential Role of Differential Phosphorylation in RNA Replication and Identification of a Genetically Flexible Domain

Nonstructural protein 5A of the hepatitis C virus (HCV) is a highly phosphorylated molecule implicated in multiple interactions with the host cell and most likely involved in RNA replication. Two phosphorylated variants of NS5A have been described, designated according to their apparent molecular ma...

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Autors principals: Appel, Nicole, Pietschmann, Thomas, Bartenschlager, Ralf
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC548472/
https://ncbi.nlm.nih.gov/pubmed/15709040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.3187-3194.2005
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