Glycine Zipper Motifs in Hepatitis C Virus Nonstructural Protein 4B Are Required for the Establishment of Viral Replication Organelles

Hepatitis C virus (HCV) RNA replication occurs in tight association with remodeled host cell membranes, presenting as cytoplasmic accumulations of single-, double-, and multimembrane vesicles in infected cells. Formation of these so-called replication organelles is mediated by a complex interplay of...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Paul, David, Madan, Vanesa, Ramirez, Omar, Bencun, Maja, Stoeck, Ina Karen, Jirasko, Vlastimil, Bartenschlager, Ralf
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Genome Replication and Regulation of Viral Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790954/
https://ncbi.nlm.nih.gov/pubmed/29167346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01890-17
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