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Hepatitis C Virus NS2 Protein Is Phosphorylated by the Protein Kinase CK2 and Targeted for Degradation to the Proteasome

Hepatitis C virus (HCV) nonstructural 2 (NS2) protein is a hydrophobic transmembrane protein, described to be involved in different functions, such as apoptosis inhibition and gene transcription modulation. We investigated here NS2 protein turnover and found that NS2 was rapidly degraded by the prot...

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Detalhes bibliográficos
Main Authors: Franck, Nathalie, Le Seyec, Jacques, Guguen-Guillouzo, Christiane, Erdtmann, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548468/
https://ncbi.nlm.nih.gov/pubmed/15708989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.2700-2708.2005
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