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Hepatitis C Virus NS2 Protein Is Phosphorylated by the Protein Kinase CK2 and Targeted for Degradation to the Proteasome

Hepatitis C virus (HCV) nonstructural 2 (NS2) protein is a hydrophobic transmembrane protein, described to be involved in different functions, such as apoptosis inhibition and gene transcription modulation. We investigated here NS2 protein turnover and found that NS2 was rapidly degraded by the prot...

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Autores principales: Franck, Nathalie, Le Seyec, Jacques, Guguen-Guillouzo, Christiane, Erdtmann, Lars
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC548468/
https://ncbi.nlm.nih.gov/pubmed/15708989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.2700-2708.2005
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