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Hepatitis C Virus NS2 Protein Is Phosphorylated by the Protein Kinase CK2 and Targeted for Degradation to the Proteasome

Hepatitis C virus (HCV) nonstructural 2 (NS2) protein is a hydrophobic transmembrane protein, described to be involved in different functions, such as apoptosis inhibition and gene transcription modulation. We investigated here NS2 protein turnover and found that NS2 was rapidly degraded by the prot...

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Sonraí Bibleagrafaíochta
Main Authors: Franck, Nathalie, Le Seyec, Jacques, Guguen-Guillouzo, Christiane, Erdtmann, Lars
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC548468/
https://ncbi.nlm.nih.gov/pubmed/15708989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.2700-2708.2005
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