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Skeletal Dysplasia Mutations Effect on Human Filamins’ Structure and Mechanosensing

Cells’ ability to sense mechanical cues in their environment is crucial for fundamental cellular processes, leading defects in mechanosensing to be linked to many diseases. The actin cross-linking protein Filamin has an important role in the conversion of mechanical forces into biochemical signals....

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Seppälä, Jonne, Bernardi, Rafael C., Haataja, Tatu J. K., Hellman, Maarit, Pentikäinen, Olli T., Schulten, Klaus, Permi, Perttu, Ylänne, Jari, Pentikäinen, Ulla
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484675/
https://ncbi.nlm.nih.gov/pubmed/28652603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04441-x
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