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Skeletal Dysplasia Mutations Effect on Human Filamins’ Structure and Mechanosensing
Cells’ ability to sense mechanical cues in their environment is crucial for fundamental cellular processes, leading defects in mechanosensing to be linked to many diseases. The actin cross-linking protein Filamin has an important role in the conversion of mechanical forces into biochemical signals....
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Publié dans: | Sci Rep |
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Auteurs principaux: | , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Nature Publishing Group UK
2017
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484675/ https://ncbi.nlm.nih.gov/pubmed/28652603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04441-x |
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