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Expression, Purification and Crystallisation of the Adenosine A(2A) Receptor Bound to an Engineered Mini G Protein
G protein-coupled receptors (GPCRs) promote cytoplasmic signalling by activating heterotrimeric G proteins in response to extracellular stimuli such as light, hormones and nucleosides. Structure determination of GPCR–G protein complexes is central to understanding the precise mechanism of signal tra...
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| Publicado no: | Bio Protoc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bio-Protocol
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484405/ https://ncbi.nlm.nih.gov/pubmed/28660236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2234 |
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