HDAC5 controls the functions of Foxp3(+) T-regulatory and CD8(+) T cells

Histone/protein deacetylases (HDACs) are frequently upregulated in human malignancies and have therefore become therapeutic targets in cancer therapy. However, inhibiting certain HDAC isoforms can have pro-tolerogenic effects on the immune system, which could make it easier for tumor cells to evade...

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Publicado en:Int J Cancer
Main Authors: Xiao, Haiyan, Jiao, Jing, Wang, Liqing, O’Brien, Shaun, Newick, Kheng, Wang, Liang-Chuan S., Falkensammer, Eva, Liu, Yujie, Han, Rongxiang, Kapoor, Veena, Hansen, Finn K., Kurz, Thomas, Hancock, Wayne W., Beier, Ulf H.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484398/
https://ncbi.nlm.nih.gov/pubmed/26704363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29979
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