Discovery of a proteinaceous cellular receptor for a norovirus

Human noroviruses (NoV) are a leading cause of gastroenteritis globally, yet host factors required for NoV infection are poorly understood. We identified host molecules essential for murine NoV (MNoV) induced cell death including CD300lf as a proteinaceous receptor. CD300lf is essential for MNoV bin...

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Publicado en:Science
Main Authors: Orchard, Robert C., Wilen, Craig B., Doench, John G., Baldridge, Megan T., McCune, Broc T., Lee, Ying-Chiang J., Lee, Sanghyun, Pruett-Miller, Shondra M., Nelson, Christopher A., Fremont, Daved H., Virgin, Herbert W.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484048/
https://ncbi.nlm.nih.gov/pubmed/27540007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf1220
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