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Gene trap and gene inversion methods for conditional gene inactivation in the mouse

Conditional inactivation of individual genes in mice using site-specific recombinases is an extremely powerful method for determining the complex roles of mammalian genes in developmental and tissue-specific contexts, a major goal of post-genomic research. However, the process of generating mice wit...

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Detalhes bibliográficos
Main Authors: Xin, Hong-Bo, Deng, Ke-Yu, Shui, Bo, Qu, Shimian, Sun, Qi, Lee, Jane, Greene, Kai Su, Wilson, Jason, Yu, Ying, Feldman, Morris, Kotlikoff, Michael I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548374/
https://ncbi.nlm.nih.gov/pubmed/15659575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni016
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