Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells

Promoterless gene trap vectors have been widely used for high-efficiency gene targeting and random mutagenesis in embryonic stem (ES) cells. Unfortunately, such vectors are only effective for genes expressed in ES cells and this has prompted the development of expression-independent vectors. These p...

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Detaylı Bibliyografya
Asıl Yazarlar: Tsakiridis, Anestis, Tzouanacou, Elena, Rahman, Afifah, Colby, Douglas, Axton, Richard, Chambers, Ian, Wilson, Valerie, Forrester, Lesley, Brickman, Joshua M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Methods Online
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770648/
https://ncbi.nlm.nih.gov/pubmed/19692586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp640
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