Evaluating Mendelian nephrotic syndrome genes for evidence of risk alleles or oligogenicity that explain heritability

BACKGROUND: More than 30 genes can harbor rare exonic variants sufficient to cause nephrotic syndrome (NS), and the number of genes implicated in monogenic NS continues to grow. However, outside the first year of life, the majority of affected patients, particularly in ancestrally mixed populations,...

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Bibliographic Details
Published in:Pediatr Nephrol
Main Authors: Crawford, Brendan D., Gillies, Christopher E., Robertson, Catherine C., Kretzler, Matthias, Otto, Edgar, Vega-Wagner, Virginia, Sampson, Matthew G.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483602/
https://ncbi.nlm.nih.gov/pubmed/27766458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-016-3513-3
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