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Evaluating Mendelian nephrotic syndrome genes for evidence of risk alleles or oligogenicity that explain heritability

BACKGROUND: More than 30 genes can harbor rare exonic variants sufficient to cause nephrotic syndrome (NS), and the number of genes implicated in monogenic NS continues to grow. However, outside the first year of life, the majority of affected patients, particularly in ancestrally mixed populations,...

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Detaylı Bibliyografya
Yayımlandı:Pediatr Nephrol
Asıl Yazarlar: Crawford, Brendan D., Gillies, Christopher E., Robertson, Catherine C., Kretzler, Matthias, Otto, Edgar, Vega-Wagner, Virginia, Sampson, Matthew G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483602/
https://ncbi.nlm.nih.gov/pubmed/27766458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-016-3513-3
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