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Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport

Ion transporters and channels are able to identify and act on specific substrates among myriads of ions and molecules critical to cellular processes, such as homeostasis, cell signalling, nutrient influx and drug efflux. Recently, we designed Rocker, a minimalist model for Zn(2+)/H(+) co-transport....

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Bibliographic Details
Published in:Philos Trans R Soc Lond B Biol Sci
Main Authors: Joh, Nathan H., Grigoryan, Gevorg, Wu, Yibing, DeGrado, William F.
Format: Artigo
Language:Inglês
Published: The Royal Society 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483517/
https://ncbi.nlm.nih.gov/pubmed/28630154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0214
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