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Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport

Ion transporters and channels are able to identify and act on specific substrates among myriads of ions and molecules critical to cellular processes, such as homeostasis, cell signalling, nutrient influx and drug efflux. Recently, we designed Rocker, a minimalist model for Zn(2+)/H(+) co-transport....

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Philos Trans R Soc Lond B Biol Sci
Main Authors: Joh, Nathan H., Grigoryan, Gevorg, Wu, Yibing, DeGrado, William F.
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483517/
https://ncbi.nlm.nih.gov/pubmed/28630154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0214
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