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Assembly mechanism of the α-pore–forming toxin cytolysin A from Escherichia coli

The cytolytic toxin cytolysin A (ClyA) from Escherichia coli is probably one of the best-characterized examples of bacterial, α-pore–forming toxins (α-PFTs). Like other PFTs, ClyA exists in a soluble, monomeric form that assembles to an annular, homo-oligomeric pore complex upon contact with deterge...

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Foilsithe in:Philos Trans R Soc Lond B Biol Sci
Main Authors: Roderer, Daniel, Glockshuber, Rudi
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Royal Society 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483514/
https://ncbi.nlm.nih.gov/pubmed/28630151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0211
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