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Effects of familial hemiplegic migraine type 1 mutations on neuronal P/Q-type Ca(2+) channel activity and inhibitory synaptic transmission
Inhibitory synapses play key roles in the modulatory circuitry that regulates pain signaling and generation of migraine headache. A rare, dominant form of this common disease, familial hemiplegic migraine type 1 (FHM1), arises from missense mutations in the pore-forming α(1A) subunit of P/Q-type Ca(...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548328/ https://ncbi.nlm.nih.gov/pubmed/15699344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409896102 |
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