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Effects of familial hemiplegic migraine type 1 mutations on neuronal P/Q-type Ca(2+) channel activity and inhibitory synaptic transmission

Inhibitory synapses play key roles in the modulatory circuitry that regulates pain signaling and generation of migraine headache. A rare, dominant form of this common disease, familial hemiplegic migraine type 1 (FHM1), arises from missense mutations in the pore-forming α(1A) subunit of P/Q-type Ca(...

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Hlavní autoři: Cao, Yu-Qing, Tsien, Richard W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC548328/
https://ncbi.nlm.nih.gov/pubmed/15699344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409896102
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