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Impact of the leaner P/Q-type Ca(2+) channel mutation on excitatory synaptic transmission in cerebellar Purkinje cells
Loss-of-function mutations in the gene encoding P/Q-type Ca(2+) channels cause cerebellar ataxia in mice and humans, but the underlying mechanism(s) are unknown. These Ca(2+) channels play important roles in regulating both synaptic transmission and intrinsic membrane properties, and defects in eith...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614031/ https://ncbi.nlm.nih.gov/pubmed/18669535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.156232 |
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