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Impact of the leaner P/Q-type Ca(2+) channel mutation on excitatory synaptic transmission in cerebellar Purkinje cells

Loss-of-function mutations in the gene encoding P/Q-type Ca(2+) channels cause cerebellar ataxia in mice and humans, but the underlying mechanism(s) are unknown. These Ca(2+) channels play important roles in regulating both synaptic transmission and intrinsic membrane properties, and defects in eith...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Shaolin, Friel, David D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614031/
https://ncbi.nlm.nih.gov/pubmed/18669535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.156232
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