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Enhanced Synaptic Inhibition Disrupts the Efferent Code of Cerebellar Purkinje Neurons in Leaner Ca(v)2.1 Ca(2+) Channel Mutant Mice

Cerebellar Purkinje cells (PCs) encode afferent information in the rate and temporal structure of their spike trains. Both spontaneous firing in these neurons and its modulation by synaptic inputs depend on Ca(2+) current carried by Ca(v)2.1 (P/Q) type channels. Previous studies have described how l...

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Main Authors: Ovsepian, Saak V., Friel, David D.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627404/
https://ncbi.nlm.nih.gov/pubmed/20845003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12311-010-0210-9
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