The R-enantiomer of the nonsteroidal antiinflammatory drug etodolac binds retinoid X receptor and induces tumor-selective apoptosis

Prostate cancer is often slowly progressive, and it can be difficult to treat with conventional cytotoxic drugs. Nonsteroidal antiinflammatory drugs inhibit the development of prostate cancer, but the mechanism of chemoprevention is unknown. Here, we show that the R-enantiomer of the nonsteroidal an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kolluri, Siva Kumar, Corr, Maripat, James, Sharon Y., Bernasconi, Michele, Lu, Desheng, Liu, Wen, Cottam, Howard B., Leoni, Lorenzo M., Carson, Dennis A., Zhang, Xiao-kun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2005
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC548323/
https://ncbi.nlm.nih.gov/pubmed/15699354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409721102
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg