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SlgA, encoded by the homolog of the human schizophrenia-associated gene PRODH, acts in clock neurons to regulate Drosophila aggression

Mutations in the proline dehydrogenase gene PRODH are linked to behavioral alterations in schizophrenia and as part of DiGeorge and velo-cardio-facial syndromes, but the role of PRODH in their etiology remains unclear. Here, we establish a Drosophila model to study the role of PRODH in behavioral di...

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Bibliographische Detailangaben
Veröffentlicht in:Dis Model Mech
Hauptverfasser: Zwarts, Liesbeth, Vulsteke, Veerle, Buhl, Edgar, Hodge, James J. L., Callaerts, Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483002/
https://ncbi.nlm.nih.gov/pubmed/28331058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.027151
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