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SlgA, encoded by the homolog of the human schizophrenia-associated gene PRODH, acts in clock neurons to regulate Drosophila aggression

Mutations in the proline dehydrogenase gene PRODH are linked to behavioral alterations in schizophrenia and as part of DiGeorge and velo-cardio-facial syndromes, but the role of PRODH in their etiology remains unclear. Here, we establish a Drosophila model to study the role of PRODH in behavioral di...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Zwarts, Liesbeth, Vulsteke, Veerle, Buhl, Edgar, Hodge, James J. L., Callaerts, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483002/
https://ncbi.nlm.nih.gov/pubmed/28331058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.027151
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