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SlgA, encoded by the homolog of the human schizophrenia-associated gene PRODH, acts in clock neurons to regulate Drosophila aggression

Mutations in the proline dehydrogenase gene PRODH are linked to behavioral alterations in schizophrenia and as part of DiGeorge and velo-cardio-facial syndromes, but the role of PRODH in their etiology remains unclear. Here, we establish a Drosophila model to study the role of PRODH in behavioral di...

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Dettagli Bibliografici
Pubblicato in:Dis Model Mech
Autori principali: Zwarts, Liesbeth, Vulsteke, Veerle, Buhl, Edgar, Hodge, James J. L., Callaerts, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483002/
https://ncbi.nlm.nih.gov/pubmed/28331058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.027151
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