MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma

Despite the importance of the RAS-RAF-MAPK pathway in normal physiology and disease of numerous organs, its role during pituitary development and tumourigenesis remains largely unknown. Here, we show that the over-activation of the MAPK pathway, through conditional expression of the gain-of-function...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Development
Main Authors: Haston, Scott, Pozzi, Sara, Carreno, Gabriela, Manshaei, Saba, Panousopoulos, Leonidas, Gonzalez-Meljem, Jose Mario, Apps, John R., Virasami, Alex, Thavaraj, Selvam, Gutteridge, Alice, Forshew, Tim, Marais, Richard, Brandner, Sebastian, Jacques, Thomas S., Andoniadou, Cynthia L., Martinez-Barbera, Juan Pedro
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2017
Teme:
Stem Cells and Regeneration
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482995/
https://ncbi.nlm.nih.gov/pubmed/28506993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.150490
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki