SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma

Pharmacological inhibition of the sonic hedgehog (SHH) pathway can be beneficial against certain cancers but detrimental in others. Adamantinomatous craniopharyngioma (ACP) is a relevant pituitary tumour, affecting children and adults, that is associated with high morbidity and increased mortality i...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Carreno, G, Boult, J K R, Apps, J, Gonzalez-Meljem, J M, Haston, S, Guiho, R, Stache, C, Danielson, L S, Koers, A, Smith, L M, Virasami, A, Panousopoulos, L, Buchfelder, M, Jacques, T S, Chesler, L, Robinson, S P, Martinez-Barbera, J P
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378366/
https://ncbi.nlm.nih.gov/pubmed/30645190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-18-0538
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