Senescence drives non-cell autonomous tumorigenesis in the pituitary gland

Por Gonzalez-Meljem, Jose Mario, Martinez-Barbera, Juan Pedro
Publicado no Mol Cell Oncol (2018)

Paracrine roles of cellular senescence in promoting tumourigenesis

Por Gonzalez-Meljem, Jose Mario, Apps, John Richard, Fraser, Helen Christina, Martinez-Barbera, Juan Pedro
Publicado no Br J Cancer (2018)

Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors

Por Carreno, Gabriela, Apps, John R., Lodge, Emily J., Panousopoulos, Leonidas, Haston, Scott, Gonzalez-Meljem, Jose Mario, Hahn, Heidi, Andoniadou, Cynthia L., Martinez-Barbera, Juan Pedro
Publicado no Development (2017)

SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer

Por Tordella, Luca, Khan, Sadaf, Hohmeyer, Anja, Banito, Ana, Klotz, Sabrina, Raguz, Selina, Martin, Nadine, Dhamarlingam, Gopuraja, Carroll, Thomas, González Meljem, José Mario, Deswal, Sumit, Martínez-Barbera, Juan Pedro, García-Escudero, Ramón, Zuber, Johannes, Zender, Lars, Gil, Jesús
Publicado no Genes Dev (2016)

MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma

Por Haston, Scott, Pozzi, Sara, Carreno, Gabriela, Manshaei, Saba, Panousopoulos, Leonidas, Gonzalez-Meljem, Jose Mario, Apps, John R., Virasami, Alex, Thavaraj, Selvam, Gutteridge, Alice, Forshew, Tim, Marais, Richard, Brandner, Sebastian, Jacques, Thomas S., Andoniadou, Cynthia L., Martinez-Barbera, Juan Pedro
Publicado no Development (2017)

Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma

Por Gonzalez-Meljem, Jose Mario, Haston, Scott, Carreno, Gabriela, Apps, John R., Pozzi, Sara, Stache, Christina, Kaushal, Grace, Virasami, Alex, Panousopoulos, Leonidas, Mousavy-Gharavy, Seyedeh Neda, Guerrero, Ana, Rashid, Mamunur, Jani, Nital, Goding, Colin R., Jacques, Thomas S., Adams, David J., Gil, Jesus, Andoniadou, Cynthia L., Martinez-Barbera, Juan Pedro
Publicado no Nat Commun (2017)

Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma

Por Donson, Andrew M, Apps, John, Griesinger, Andrea M, Amani, Vladimir, Witt, Davis A, Anderson, Richard C E, Niazi, Toba N, Grant, Gerald, Souweidane, Mark, Johnston, James M, Jackson, Eric M, Kleinschmidt-DeMasters, Bette K, Handler, Michael H, Tan, Aik-Choon, Gore, Lia, Virasami, Alex, Gonzalez-Meljem, Jose Mario, Jacques, Thomas S, Martinez-Barbera, Juan Pedro, Foreman, Nicholas K, Hankinson, Todd C
Publicado no J Neuropathol Exp Neurol (2017)

Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pa...

Por Apps, John R., Carreno, Gabriela, Gonzalez-Meljem, Jose Mario, Haston, Scott, Guiho, Romain, Cooper, Julie E., Manshaei, Saba, Jani, Nital, Hölsken, Annett, Pettorini, Benedetta, Beynon, Robert J., Simpson, Deborah M., Fraser, Helen C., Hong, Ying, Hallang, Shirleen, Stone, Thomas J., Virasami, Alex, Donson, Andrew M., Jones, David, Aquilina, Kristian, Spoudeas, Helen, Joshi, Abhijit R., Grundy, Richard, Storer, Lisa C. D., Korbonits, Márta, Hilton, David A., Tossell, Kyoko, Thavaraj, Selvam, Ungless, Mark A., Gil, Jesus, Buslei, Rolf, Hankinson, Todd, Hargrave, Darren, Goding, Colin, Andoniadou, Cynthia L., Brogan, Paul, Jacques, Thomas S., Williams, Hywel J., Martinez-Barbera, Juan Pedro
Publicado no Acta Neuropathol (2018)