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RET-mediated glial cell line-derived neurotrophic factor signaling inhibits mouse prostate development

In humans and rodents, the prostate gland develops from the embryonic urogenital sinus (UGS). The androgen receptor (AR) is thought to control the expression of morphogenetic genes in inductive UGS mesenchyme, which promotes proliferation and cytodifferentiation of the prostatic epithelium. However,...

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Bibliographic Details
Published in:Development
Main Authors: Park, Hyun-Jung, Bolton, Eric C.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482989/
https://ncbi.nlm.nih.gov/pubmed/28506996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.145086
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