ChIP-seq analysis of genomic binding regions of five major transcription factors highlights a central role for ZIC2 in the mouse epiblast stem cell gene regulatory network

To obtain insight into the transcription factor (TF)-dependent regulation of epiblast stem cells (EpiSCs), we performed ChIP-seq analysis of the genomic binding regions of five major TFs. Analysis of in vivo biotinylated ZIC2, OTX2, SOX2, POU5F1 and POU3F1 binding in EpiSCs identified several new fe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Development
Egile Nagusiak: Matsuda, Kazunari, Mikami, Tomoyuki, Oki, Shinya, Iida, Hideaki, Andrabi, Munazah, Boss, Jeremy M., Yamaguchi, Katsushi, Shigenobu, Shuji, Kondoh, Hisato
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Ltd 2017
Gaiak:
Stem Cells and Regeneration
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482983/
https://ncbi.nlm.nih.gov/pubmed/28455373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143479
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