ChIP-seq analysis of genomic binding regions of five major transcription factors highlights a central role for ZIC2 in the mouse epiblast stem cell gene regulatory network

To obtain insight into the transcription factor (TF)-dependent regulation of epiblast stem cells (EpiSCs), we performed ChIP-seq analysis of the genomic binding regions of five major TFs. Analysis of in vivo biotinylated ZIC2, OTX2, SOX2, POU5F1 and POU3F1 binding in EpiSCs identified several new fe...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Matsuda, Kazunari, Mikami, Tomoyuki, Oki, Shinya, Iida, Hideaki, Andrabi, Munazah, Boss, Jeremy M., Yamaguchi, Katsushi, Shigenobu, Shuji, Kondoh, Hisato
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482983/
https://ncbi.nlm.nih.gov/pubmed/28455373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143479
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