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Electroporation as a vaccine delivery system and a natural adjuvant to intradermal administration of plasmid DNA in macaques
In vivo electroporation (EP) is used to enhance the uptake of nucleic acids and its association with DNA vaccination greatly stimulates immune responses to vaccine antigens delivered through the skin. However, the effect of EP on cutaneous cell behavior, the dynamics of immune cell recruitment and l...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482824/ https://ncbi.nlm.nih.gov/pubmed/28646234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04547-2 |
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