Innate Molecular and Cellular Signature in the Skin Preceding Long-Lasting T Cell Responses after Electroporated DNA Vaccination

DNA vaccines delivered with electroporation (EP) have shown promising results in preclinical models and are evaluated in clinical trials. In this study, we aim to characterize early mechanisms occurring in the skin after intradermal injection and EP of the auxoGTUmultiSIV DNA vaccine in nonhuman pri...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Adam, Lucille, Tchitchek, Nicolas, Todorova, Biliana, Rosenbaum, Pierre, Joly, Candie, Poux, Candice, Chapon, Catherine, Spetz, Anna-Lena, Ustav, Mart, Le Grand, Roger, Martinon, Frédéric
Format: Artigo
Sprog:Inglês
Udgivet: AAI 2020
Fag:
Systems Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276943/
https://ncbi.nlm.nih.gov/pubmed/32385135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900517
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