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Insulin growth factor binding protein 2 mediates the progression of lymphangioleiomyomatosis
Lymphangioleiomyomatosis (LAM) is a progressive pulmonary disease that almost exclusively affects women. LAM cells migrate to the lungs, where they cause cystic destruction of lung parenchyma. Mutations in TSC1 or TSC2 lead to the activation of the mammalian target of rapamycin complex-1, a kinase t...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482682/ https://ncbi.nlm.nih.gov/pubmed/28410230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16695 |
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