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Expression of embryonal stem cell transcription factors in breast cancer: Oct4 as an indicator for poor clinical outcome and tamoxifen resistance

The transcription factors of embryonic stem cells, such as Oct4, Sox2, Nanog, Bmi1, and Klf4, are known to be associated with stemness, epithelial–mesenchymal transition and aggressive tumor behavior. This study was designed to evaluate the clinicopathological significance of their expression in bre...

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Publicado en:Oncotarget
Autores principales: Gwak, Jae Moon, Kim, Milim, Kim, Hyun Jeong, Jang, Min Hye, Park, So Yeon
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482656/
https://ncbi.nlm.nih.gov/pubmed/28422735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16750
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