Cyclin-dependent kinase 1 activity coordinates the chromatin associated state of Oct4 during cell cycle in embryonic stem cells

Cyclin-dependent kinase 1 (Cdk1) is indispensable for embryonic stem cell (ESC) maintenance and embryo development. Even though some reports have described a connection between Cdk1 and Oct4, there is no evidence that Cdk1 activity is directly linked to the ESC pluripotency transcription program. We...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Kim, Hye Ji, Shin, Jihoon, Lee, Sangho, Kim, Tae Wan, Jang, Hyonchol, Suh, Min Young, Kim, Jae-Hwan, Hwang, In-Young, Hwang, Deog Su, Cho, Eun-Jung, Youn, Hong-Duk
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061841/
https://ncbi.nlm.nih.gov/pubmed/29901724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky371
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