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Expression of embryonal stem cell transcription factors in breast cancer: Oct4 as an indicator for poor clinical outcome and tamoxifen resistance

The transcription factors of embryonic stem cells, such as Oct4, Sox2, Nanog, Bmi1, and Klf4, are known to be associated with stemness, epithelial–mesenchymal transition and aggressive tumor behavior. This study was designed to evaluate the clinicopathological significance of their expression in bre...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Gwak, Jae Moon, Kim, Milim, Kim, Hyun Jeong, Jang, Min Hye, Park, So Yeon
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482656/
https://ncbi.nlm.nih.gov/pubmed/28422735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16750
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