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TRPA1 and TRPV1 contribute to propofol-mediated antagonism of U46619-induced constriction in murine coronary arteries

BACKGROUND: Transient receptor potential (TRP) ion channels have emerged as key components contributing to vasoreactivity. Propofol, an anesthetic is associated with adverse side effects including hypotension and acute pain upon infusion. Our objective was to determine the extent to which TRPA1 and/...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Sinharoy, Pritam, Bratz, Ian N., Sinha, Sayantani, Showalter, Loral E., Andrei, Spencer R., Damron, Derek S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482493/
https://ncbi.nlm.nih.gov/pubmed/28644897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180106
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