TRPA1 and TRPV1 contribute to propofol-mediated antagonism of U46619-induced constriction in murine coronary arteries

BACKGROUND: Transient receptor potential (TRP) ion channels have emerged as key components contributing to vasoreactivity. Propofol, an anesthetic is associated with adverse side effects including hypotension and acute pain upon infusion. Our objective was to determine the extent to which TRPA1 and/...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Sinharoy, Pritam, Bratz, Ian N., Sinha, Sayantani, Showalter, Loral E., Andrei, Spencer R., Damron, Derek S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482493/
https://ncbi.nlm.nih.gov/pubmed/28644897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180106
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