iPSC-derived human microglia-like cells to study neurological diseases

Microglia play critical roles in brain development, homeostasis, and neurological disorders. Here, we report that human microglial-like cells (iMGL) can be differentiated from iPSCs to study their function in neurological diseases, like Alzheimer’s disease (AD). We find that iMGLs develop in vitro s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuron
मुख्य लेखकों: Abud, Edsel M., Ramirez, Ricardo N., Martinez, Eric S., Healy, Luke M., Nguyen, Cecilia H.H., Newman, Sean A., Yeromin, Andriy V., Scarfone, Vanessa M., Marsh, Samuel E., Fimbres, Cristhian, Caraway, Chad A., Fote, Gianna M., Madany, Abdullah M., Agrawal, Anshu, Kayed, Rakez, Gylys, Karen H., Cahalan, Michael D., Cummings, Brian J., Antel, Jack P., Mortazavi, Ali, Carson, Monica J., Poon, Wayne W., Blurton-Jones, Mathew
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482419/
https://ncbi.nlm.nih.gov/pubmed/28426964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.03.042
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