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Resolving sub-cellular miRNA trafficking and turnover at single-molecule resolution
Regulation of miRNA localization and stability is critical for their extensive cytoplasmic RNA silencing activity and emerging nuclear functions. Here, we have developed single-molecule fluorescence-based tools to assess the sub-cellular trafficking, integrity and activity of miRNAs. We find that se...
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| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482240/ https://ncbi.nlm.nih.gov/pubmed/28423324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.03.075 |
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