Nrf2 mediates the protective effects of homocysteine by increasing the levels of GSH content in HepG2 cells

Homocysteine (Hcy) and glutathione (GSH) are crucial reduction-oxidation mediators. The underlying mechanisms governing the effects of Hcy on GSH generation in the progression of alcoholic liver disease has so far received little attention. The present study hypothesized that the antioxidant transcr...

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Veröffentlicht in:Mol Med Rep
Hauptverfasser: Zhang, Bing, Dong, Jing-Lin, Chen, Ying-Li, Liu, Yang, Huang, Shi-Shun, Zhong, Xiu-Li, Cheng, Yu-Hong, Wang, Zhi-Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482120/
https://ncbi.nlm.nih.gov/pubmed/28560453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6633
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