Homocysteine Induces Heme Oxygenase-1 Expression via Transcription Factor Nrf2 Activation in HepG2 Cells

Background: Elevated level of plasma homocysteine has been related to various diseases. Patients with hyperhomocysteinemia can develop hepatic steatosis and fibrosis. We hypothesized that oxidative stress induced by homocysteine might play an important role in pathogenesis of liver injury. Also, the...

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Detaylı Bibliyografya
Asıl Yazarlar: Mani, Monireh, Golmohammadi, Taghi, Khaghani, Shahnaz, Zamani, Zahra, Azadmanesh, Kayhan, Meshkani, Reza, Pasalar, Parvin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Pasteur Institute Of Iran 2013
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677675/
https://ncbi.nlm.nih.gov/pubmed/23567851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6091/ibj.1158.2013
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