Nrf2 mediates the protective effects of homocysteine by increasing the levels of GSH content in HepG2 cells

Homocysteine (Hcy) and glutathione (GSH) are crucial reduction-oxidation mediators. The underlying mechanisms governing the effects of Hcy on GSH generation in the progression of alcoholic liver disease has so far received little attention. The present study hypothesized that the antioxidant transcr...

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Gepubliceerd in:Mol Med Rep
Hoofdauteurs: Zhang, Bing, Dong, Jing-Lin, Chen, Ying-Li, Liu, Yang, Huang, Shi-Shun, Zhong, Xiu-Li, Cheng, Yu-Hong, Wang, Zhi-Gang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482120/
https://ncbi.nlm.nih.gov/pubmed/28560453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6633
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