Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC

Cancer chemoresistance and metastasis are tightly associated features. However, whether they share common molecular mechanisms and thus can be targeted with one common strategy remain unclear in non-small cell lung cancer (NSCLC). Here, we report that high levels of microRNA-128-3p (miR-128-3p) is k...

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Publicat a:Nat Commun
Autors principals: Cai, Junchao, Fang, Lishan, Huang, Yongbo, Li, Rong, Xu, Xiaonan, Hu, Zhihuang, Zhang, Le, Yang, Yi, Zhu, Xun, Zhang, Heng, Wu, Jueheng, Huang, Yan, Li, Jun, Zeng, Musheng, Song, Erwei, He, Yukai, Zhang, Li, Li, Mengfeng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481840/
https://ncbi.nlm.nih.gov/pubmed/28627514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15870
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