EGF-induced nuclear localization of SHCBP1 activates β-catenin signaling and promotes cancer progression

Aberrant activation of EGFR represents a common event in non-small cell lung carcinoma (NSCLC) and activates various downstream signaling pathways. While EGFR activation of β-catenin signaling was previously reported, the mediating mechanism remains unclear. Our current study found that EGFR activat...

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Pubblicato in:Oncogene
Autori principali: Liu, Lei, Yang, Yi, Liu, Shihua, Tao, Tianyu, Cai, Junchao, Wu, Jueheng, Guan, Hongyu, Zhu, Xun, He, Zhenjian, Li, Jun, Song, Erwei, Zeng, Musheng, Li, Mengfeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355651/
https://ncbi.nlm.nih.gov/pubmed/30177836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0473-z
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