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Francisella requires dynamic type VI secretion system and ClpB to deliver effectors for phagosomal escape

Francisella tularensis is an intracellular pathogen that causes the fatal zoonotic disease tularaemia. Critical for its pathogenesis is the ability of the phagocytosed bacteria to escape into the cell cytosol. For this, the bacteria use a non-canonical type VI secretion system (T6SS) encoded on the...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Brodmann, Maj, Dreier, Roland F., Broz, Petr, Basler, Marek
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481754/
https://ncbi.nlm.nih.gov/pubmed/28621333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15853
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