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Altered Microtubule Dynamics in Neurodegenerative Disease: Therapeutic Potential of Microtubule-Stabilizing Drugs

Many neurodegenerative diseases are characterized by deficiencies in neuronal axonal transport, a process in which cellular cargo is shuttled with the aid of molecule motors from the cell body to axonal termini and back along microtubules (MTs). Proper axonal transport is critical to the normal func...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Brunden, Kurt R., Lee, Virginia M-Y., Smith, Amos B., Trojanowski, John Q., Ballatore, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481496/
https://ncbi.nlm.nih.gov/pubmed/28012891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.12.021
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