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In silico Discovery of Novel FXa Inhibitors by Pharmacophore Modeling and Molecular Docking
ABSTRACT: Coagulation Factor Xa (FXa) is the crucial enzyme at the convergent point of the intrinsic and extrinsic coagulation pathways. The inhibition of FXa is an effective approach against thrombotic diseases. In the present study, a specific strategy is reported to discover 10 novel FXa inhibito...
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| Publicado no: | Nat Prod Bioprospect |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Singapore
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5481271/ https://ncbi.nlm.nih.gov/pubmed/28577290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13659-017-0126-x |
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